August 15, 2026 
6 min read
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NB MEDICAL | ADVANCING REGENERATIVE SOLUTIONS
PRP and PRF at the Point of Care
By Dr. William “Wes” Alden • Based on Nature Communications (Aug 2026) • 5 min read
The B8500 System: a practical, portable platform for preparing and customizing autologous biologics in your practice
A physician resource from NB Medical
Platelet rich plasma (PRP) and platelet rich fibrin (PRF) have moved from specialized centers into everyday practice across wound care, orthopedics, dermatology, and aesthetics. Patients increasingly ask for regenerative options that use their own biology, and clinicians increasingly want to offer them. For many practices the obstacle has not been interest, but workflow: the equipment, the disposables, and the time it takes to prepare a consistent product at the chairside. The NB Medical B8500 was built to remove that obstacle and make point of care PRP and PRF practical for the modern practice.
A Brief Refresher on PRP and PRF
Both preparations begin with a small draw of the patient’s own blood, concentrated by centrifugation. Platelets are not only the cells that stop bleeding; they are reservoirs of the growth factors that orchestrate tissue repair, including platelet derived growth factor, transforming growth factor beta, vascular endothelial growth factor, and epidermal and insulin like growth factors. Concentrating them lets a clinician place a strong, physiologic repair signal exactly where it is needed.
PRP, the first generation preparation, is typically processed to stay liquid and releases its growth factors relatively quickly. PRF, the second generation refinement, is spun without anticoagulant so the blood begins its natural clotting, producing a soft fibrin scaffold that traps platelets and white cells and releases growth factors slowly over days. In practice, PRP behaves like a concentrated injection, while PRF behaves like a living, autologous scaffold prepared from the patient in the room. Both are autologous, which gives them an excellent safety profile.
Where Physicians Are Using PRP and PRF
The clinical footprint is broad, and the evidence is strongest in several well studied areas. Presenting these honestly is part of building durable patient trust.In orthopedics, where the human evidence is deepest, PRP is widely used for knee osteoarthritis and chronic tendon conditions such as tennis elbow, with a substantial body of trials supporting its use, including studies comparing it favorably to hyaluronic acid in earlier stage knee arthritis. In dermatology, PRP has become one of the better supported regenerative options for pattern hair thinning and is used with microneedling for skin quality and scarring. In wound care, concentrated autologous growth factors, ideally in the sustained release form of PRF, serve as an adjunct for hard to heal chronic wounds. In aesthetics, PRF has become popular for facial rejuvenation and delicate areas because of its scaffold and slower growth factor release, with a younger but growing evidence base. Across all of these, technique and consistency of preparation are central to results, which is exactly where a reliable, standardized platform matters.
One Platform, Customizable Protocols
The B8500 is more than a centrifuge. It is a PRP, PRF, and infusion system, which lets clinicians combine the autologous biologic with selected enhancements to tailor the preparation to the procedure and the patient. Enhancement options include hyaluronic acid for hydration and matrix support, calcium for fibrin activation, and vitamin C, along with additional agents used at the clinician’s discretion and in accordance with applicable regulations. That flexibility lets a single device support a range of protocols rather than locking a practice into one.
Why the B8500
The B8500 was engineered around what a busy practice actually needs: speed, consistency, portability, and a clean, closed workflow.
Because it is light and quiet, the B8500 supports care not only in the clinic but in office based and mobile settings, extending the reach of a regenerative service line to patients who cannot easily travel.
Specification | Detail |
|---|---|
Spin options | Preset one, three, and five minute cycles for PRP, PRF, and infusion protocols |
Speed | Up to approximately 5,000 RPM |
Relative centrifugal force | Up to approximately 1,200 x g, tuned for platelet and growth factor recovery |
Noise level | Under 55 decibels for quiet in office and chairside use |
Weight and portability | Approximately 10.6 pounds; lightweight for clinic, office, or mobile use |
Workflow | Simple preset controls designed to deliver a consistent preparation every time |
The Complete Supply Ecosystem
Product | Description |
|---|---|
B8500 (Buster) device | Portable PRP, PRF, and infusion platform with preset spin protocols and infusion capability. |
B-85 disposable kit | Single use, sterile, pyrogen free closed system for PRP, PRF, and infusion protocols, designed to minimize contamination risk and simplify workflow. |
Phlebotomy collection kit | Medical grade collection tray and components for a clean, standardized blood draw. |
Infusion enhancements | Hyaluronic acid, calcium, vitamin C, and additional options to customize each protocol. |
The Case for Offering PRP and PRF in Your Practice
Adding a point of care regenerative service is both a clinical and a practice building decision. Patient demand for autologous, natural options continues to grow, and the safety profile of using a patient’s own blood makes these therapies approachable for a wide range of practices.
Preparing PRP and PRF in house gives the clinician direct control over quality, timing, and protocol, rather than depending on outside processing. And because the therapy is consumable driven and often offered on a cash basis, it can support a differentiated, recurring service line that complements the care a practice already provides. The B8500 lowers the barrier to entry by making that workflow fast, portable, and consistent.
Standardized, Responsible Care
Consistency and compliance protect both patients and the practice. The B8500 is intended for use by trained healthcare professionals, and its preset protocols and closed disposable system are designed to make a standardized preparation repeatable across operators. Preparation and clinical application of autologous biologics, and any added agents, should follow each clinician’s professional judgment and all applicable laws and regulations. NB Medical provides device specifications, regulatory information, and training to support proper, standardized use.
Bring regenerative care in house with NB Medical.
To learn more about the B8500 system, request a demonstration, or place an order for devices and supplies, contact our team.
NB Medical | Advancing Regenerative Solutions
Phone: (855) 623-9342 Email: info@nbmedical.com Web: nbmedical.com
This material is intended for licensed healthcare professionals and is provided for educational and informational purposes. Clinical outcomes vary by patient, indication, and technique, and the discussion of PRP and PRF above is not a claim of guaranteed results. Contact NB Medical for full device specifications, regulatory information, and training. Any agents added to a preparation should be sourced and used in accordance with applicable laws and regulations.
